Brivaracetam population pharmacokinetics in children with epilepsy aged 1 month to 16 years

PURPOSE: The aims of the study were to develop a population pharmacokinetic model of orally administered brivaracetam in paediatric patients and to provide dosing suggestions. METHODS: Analysis included 600 brivaracetam plasma concentrations from a phase 2a study (NCT00422422; N01263) in 96 paediatr...

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Bibliographic Details
Published in:Eur J Clin Pharmacol
Main Authors: Schoemaker, Rik, Wade, Janet R, Stockis, Armel
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
Subjects:
Pharmacokinetics and Disposition
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423986/
https://ncbi.nlm.nih.gov/pubmed/28280887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-017-2230-6
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