Loading...
Obstacles posed by the tumor microenvironment to T cell activity: a case for synergistic therapies
T cell dysfunction in solid tumors results from multiple mechanisms. Altered signaling pathways in tumor cells help produce a suppressive tumor microenvironment enriched for inhibitory cells, posing a major obstacle for cancer immunity. Metabolic constraints to cell function and survival shape tumor...
Saved in:
| Published in: | Cancer Cell |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423788/ https://ncbi.nlm.nih.gov/pubmed/28292435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.02.008 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Loading...