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Polo-like kinase-dependent phosphorylation of the synaptonemal complex protein SYP-4 regulates double-strand break formation through a negative feedback loop.

The synaptonemal complex (SC) is an ultrastructurally conserved proteinaceous structure that holds homologous chromosomes together and is required for the stabilization of pairing interactions and the completion of crossover (CO) formation between homologs during meiosis I. Here, we identify a novel...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nadarajan, Saravanapriah, Lambert, Talley J, Altendorfer, Elisabeth, Gao, Jinmin, Blower, Michael D, Waters, Jennifer C, Colaiácovo, Monica P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423773/
https://ncbi.nlm.nih.gov/pubmed/28346135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23437
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