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In vitro expression of rat lens aldose reductase in Escherichia coli.

Aldose reductase (alditol:NADP+ oxidoreductase, EC 1.1.1.21), an enzyme that converts glucose to sorbitol, the first step of the polyol pathway, has been implicated in secondary complications of diabetes, such as cataracts, retinopathy, neuropathy, and nephropathy. Aldose reductase inhibitors have b...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Old, S E, Sato, S, Kador, P F, Carper, D A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54237/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2114645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.13.4942
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