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Hierarchical Models for Multiple, Rare Outcomes Using Massive Observational Healthcare Databases

Clinical trials often lack power to identify rare adverse drug events (ADEs) and therefore cannot address the threat rare ADEs pose, motivating the need for new ADE detection techniques. Emerging national patient claims and electronic health record databases have inspired post-approval early detecti...

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Detalhes bibliográficos
Publicado no:Stat Anal Data Min
Main Authors: Shaddox, Trevor R., Ryan, Patrick B., Schuemie, Martijn J., Madigan, David, Suchard, Marc A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423675/
https://ncbi.nlm.nih.gov/pubmed/28503249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sam.11324
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