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Single-molecule protein identification by sub-nanopore sensors

Recent advances in top-down mass spectrometry enabled identification of intact proteins, but this technology still faces challenges. For example, top-down mass spectrometry suffers from a lack of sensitivity since the ion counts for a single fragmentation event are often low. In contrast, nanopore t...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Kolmogorov, Mikhail, Kennedy, Eamonn, Dong, Zhuxin, Timp, Gregory, Pevzner, Pavel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423552/
https://ncbi.nlm.nih.gov/pubmed/28486472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005356
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