Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

Evidence suggests that disturbances in neurobiological mechanisms of reward and inhibitory control maintain addiction and provoke relapse during abstinence. Abnormalities within the dopamine system may contribute to these disturbances and pharmacologically targeting the D3 dopamine receptor (DRD3) i...

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Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Murphy, Anna, Nestor, Liam J, McGonigle, John, Paterson, Louise, Boyapati, Venkataramana, Ersche, Karen D, Flechais, Remy, Kuchibatla, Shankar, Metastasio, Antonio, Orban, Csaba, Passetti, Filippo, Reed, Laurence, Smith, Dana, Suckling, John, Taylor, Eleanor, Robbins, Trevor W, Lingford-Hughes, Anne, Nutt, David J, Deakin, John FW, Elliott, Rebecca
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423526/
https://ncbi.nlm.nih.gov/pubmed/28042871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.289
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