Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA

Changes in lifestyle and environmental conditions give rise to an increasing prevalence of liver and lung fibrosis, and both have a poor prognosis. Promising results have been reported for recombinant angiotensin-converting enzyme 2 (ACE2) protein administration in experimental liver and lung fibros...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Schrom, Eva, Huber, Maja, Aneja, Manish, Dohmen, Christian, Emrich, Daniela, Geiger, Johannes, Hasenpusch, Günther, Herrmann-Janson, Annika, Kretzschmann, Verena, Mykhailyk, Olga, Pasewald, Tamara, Oak, Prajakta, Hilgendorff, Anne, Wohlleber, Dirk, Hoymann, Heinz-Gerd, Schaudien, Dirk, Plank, Christian, Rudolph, Carsten, Kubisch-Dohmen, Rebekka
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423349/
https://ncbi.nlm.nih.gov/pubmed/28624211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.04.006
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