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Light-Triggerable Liposomes for Enhanced Endolysosomal Escape and Gene Silencing in PC12 Cells

Liposomes are an effective gene and/or drug delivery system, widely used in biomedical applications including gene therapy and chemotherapy. Here, we designed a photo-responsive liposome (lipVP) loaded with a photosensitizer verteporfin (VP). This photosensitizer is clinically approved for photodyna...

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Dades bibliogràfiques
Publicat a:Mol Ther Nucleic Acids
Autors principals: Chen, Wenjie, Deng, Wei, Goldys, Ewa M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423320/
https://ncbi.nlm.nih.gov/pubmed/28624212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.04.015
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