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Synthesis and Biological Evaluation of N-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)benzamide Derivatives as Lipoxygenase Inhibitor with Potential Anticancer Activity

In the recent years, the role of LOX enzymes in the origin of neoplastic diseases such as colorectal, skin, pancreatic and renal cancers has been confirmed. A new series of 1,3,4-thiadiazole derivatives bearing 2-pyridyl moiety was synthesized and the cytotoxicity of the members of this series was a...

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Foilsithe in:Iran J Pharm Res
Main Authors: Aliabadi, Alireza, Mohammadi-Farani, Ahmad, Roodabeh, Sahar, Ahmadi, Farahnaz
Formáid: Artigo
Teanga:Inglês
Foilsithe: Shaheed Beheshti University of Medical Sciences 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423244/
https://ncbi.nlm.nih.gov/pubmed/28496472
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