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Synthesis and Biological Evaluation of N-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)benzamide Derivatives as Lipoxygenase Inhibitor with Potential Anticancer Activity

In the recent years, the role of LOX enzymes in the origin of neoplastic diseases such as colorectal, skin, pancreatic and renal cancers has been confirmed. A new series of 1,3,4-thiadiazole derivatives bearing 2-pyridyl moiety was synthesized and the cytotoxicity of the members of this series was a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Iran J Pharm Res
Prif Awduron: Aliabadi, Alireza, Mohammadi-Farani, Ahmad, Roodabeh, Sahar, Ahmadi, Farahnaz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shaheed Beheshti University of Medical Sciences 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423244/
https://ncbi.nlm.nih.gov/pubmed/28496472
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