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KLK6‐regulated miRNA networks activate oncogenic pathways in breast cancer subtypes

KLK6 is expressed in normal mammary tissues and is aberrantly regulated in breast cancer. At physiological levels of expression, i.e. those found in normal mammary tissues, KLK6 acts as a tumor suppressor in human breast cancer. However, aberrant overexpression of KLK6 (i.e. 50–100‐fold higher than...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Sidiropoulos, Konstantinos G., Ding, Qiang, Pampalakis, Georgios, White, Nicole M.A., Boulos, Peter, Sotiropoulou, Georgia, Yousef, George M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423190/
https://ncbi.nlm.nih.gov/pubmed/27093921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.03.008
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