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KLK6‐regulated miRNA networks activate oncogenic pathways in breast cancer subtypes

KLK6 is expressed in normal mammary tissues and is aberrantly regulated in breast cancer. At physiological levels of expression, i.e. those found in normal mammary tissues, KLK6 acts as a tumor suppressor in human breast cancer. However, aberrant overexpression of KLK6 (i.e. 50–100‐fold higher than...

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Vydáno v:Mol Oncol
Hlavní autoři: Sidiropoulos, Konstantinos G., Ding, Qiang, Pampalakis, Georgios, White, Nicole M.A., Boulos, Peter, Sotiropoulou, Georgia, Yousef, George M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423190/
https://ncbi.nlm.nih.gov/pubmed/27093921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.03.008
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