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Indolo‐pyrido‐isoquinolin based alkaloid inhibits growth, invasion and migration of breast cancer cells via activation of p53‐miR34a axis
The tumor suppressor p53 plays a critical role in suppressing cancer growth and progression and is an attractive target for the development of new targeted therapies. We synthesized several indolo‐pyrido‐isoquinolin based alkaloids to activate p53 function and examined their therapeutic efficacy usi...
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Publicado no: | Mol Oncol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423185/ https://ncbi.nlm.nih.gov/pubmed/27259808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.04.003 |
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