Monitoring vascular normalization induced by antiangiogenic treatment with 18F‐fluoromisonidazole‐PET

Background: Rationalization of antiangiogenics requires biomarkers. Vascular re‐normalization is one widely accepted mechanism of action for this drug class. The interstitium of tumors with abnormal vasculature is hypoxic. We sought to track vascular normalization with 18F‐misonidazole ([18F]‐FMISO,...

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Gepubliceerd in:Mol Oncol
Hoofdauteurs: Hernández-Agudo, Elena, Mondejar, Tamara, Soto-Montenegro, Maria Luisa, Megías, Diego, Mouron, Silvana, Sanchez, Jesus, Hidalgo, Manuel, Lopez-Casas, Pedro Pablo, Mulero, Francisca, Desco, Manuel, Quintela-Fandino, Miguel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2015
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423153/
https://ncbi.nlm.nih.gov/pubmed/26778791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.12.011
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