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Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases

Assessing circulating tumor DNA (ctDNA) is a promising method to evaluate somatic mutations from solid tumors in a minimally‐invasive way. In a group of twelve metastatic colorectal cancer (mCRC) patients undergoing liver metastasectomy, from each patient DNA from cell‐free DNA (cfDNA), the primary...

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Vydáno v:Mol Oncol
Hlavní autoři: Beije, Nick, Helmijr, Jean C., Weerts, Marjolein J.A., Beaufort, Corine M., Wiggin, Matthew, Marziali, Andre, Verhoef, Cornelis, Sleijfer, Stefan, Jansen, Maurice P.H.M., Martens, John W.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423131/
https://ncbi.nlm.nih.gov/pubmed/28949453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.10.001
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