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Antithymocyte globulin treatment at the time of transplantation impairs donor hematopoietic stem cell engraftment

Antithymocyte globulin (ATG) is often included in the conditioning regimen to prevent graft vs. host disease in allogeneic hematopoietic stem cell (HSC) transplantation. However, because ATG contains antibodies targeting a wide range of antigens on human cells, its potential off-target effects remai...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Jin, Feng, He, Jin, Jin, Chunhui, Fan, Wei, Shan, Yanhong, Zhang, Zhefeng, Sun, Liguang, Hu, Zheng, Yang, Yong-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423086/
https://ncbi.nlm.nih.gov/pubmed/26499257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.92
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