Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy

Anti-MAG (myelin-associated glycoprotein) neuropathy is a disabling autoimmune peripheral neuropathy caused by monoclonal IgM autoantibodies that recognize the carbohydrate epitope HNK-1 (human natural killer-1). This glycoepitope is highly expressed on adhesion molecules, such as MAG, present in my...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Herrendorff, Ruben, Hänggi, Pascal, Pfister, Hélène, Yang, Fan, Demeestere, Delphine, Hunziker, Fabienne, Frey, Samuel, Schaeren-Wiemers, Nicole, Steck, Andreas J., Ernst, Beat
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2017
Ábhair:
PNAS Plus
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422814/
https://ncbi.nlm.nih.gov/pubmed/28416698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619386114
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