Matrix Metalloproteinase-1 Activation Contributes to Airway Smooth Muscle Growth and Asthma Severity

Rationale: Matrix metalloproteinase-1 (MMP-1) and mast cells are present in the airways of people with asthma. Objectives: To investigate whether MMP-1 could be activated by mast cells and increase asthma severity. Methods: Patients with stable asthma and healthy control subjects underwent spirometr...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Naveed, Shams-un-nisa, Clements, Debbie, Jackson, David J., Philp, Christopher, Billington, Charlotte K., Soomro, Irshad, Reynolds, Catherine, Harrison, Timothy W., Johnston, Sebastian L., Shaw, Dominick E., Johnson, Simon R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422648/
https://ncbi.nlm.nih.gov/pubmed/27967204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201604-0822OC
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