BRM Promoter Polymorphisms and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and CCTG BR.24 trial

INTRODUCTION: BRM, a key catalytic subunit of the SWI/SNF chromatin remodeling complex, is a putative tumor susceptibility gene that is silenced in 15% of non-small cell lung cancer (NSCLC). Two novel BRM promoter polymorphisms (BRM-741, BRM-1321) are associated with reversible epigenetic silencing...

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Publicado no:Clin Cancer Res
Main Authors: Liu, Geoffrey, Cuffe, Sinead, Liang, Shermi, Azad, Abul Kalam, Cheng, Lu, Brhane, Yonathan, Qiu, Xin, Cescon, David, Bruce, Jeffrey, Chen, Zhuo, Cheng, Dangxiao, Patel, Devalben, Tse, Brandon, Laurie, Scott A., Goss, Glenwood, Leighl, Natasha B., Hung, Rayjean, Bradbury, Penelope A., Seymour, Lesley, Shepherd, Frances A., Tsao, Ming Sound, Chen, Bingshu E., Xu, Wei, Reisman, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422138/
https://ncbi.nlm.nih.gov/pubmed/27827316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1640
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