Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf

Human microRNA-125a-5p (miR-125a) is expressed in most tissues where it downregulates the expression of membrane receptors or intracellular transductors of mitogenic signals, thus limiting cell proliferation. Expression of this miRNA generally increases with cell differentiation whereas it is downre...

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Pubblicato in:Oncotarget
Autori principali: Coppola, Nicola, de Stefano, Giorgio, Panella, Marta, Onorato, Lorenzo, Iodice, Valentina, Minichini, Carmine, Mosca, Nicola, Desiato, Luisa, Farella, Nunzia, Starace, Mario, Liorre, Giulia, Potenza, Nicoletta, Sagnelli, Evangelista, Russo, Aniello
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421930/
https://ncbi.nlm.nih.gov/pubmed/28445974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15809
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