The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma

Toll-like receptor (TLR) ligands are strongly considered immune-adjuvants for cancer immunotherapy and have been shown to exert direct anti-cancer effects. This study was performed to evaluate the synergistic anti-cancer and anti-metastatic effects of the TLR7 agonist imiquimod (IMQ) during radiothe...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cho, Jeong Hyun, Lee, Hyo-Ji, Ko, Hyun-Jeong, Yoon, Byung-Il, Choe, Jongseon, Kim, Keun-Cheol, Hahn, Tae-Wook, Han, Jeong A., Choi, Sun Shim, Jung, Young Mee, Lee, Kee-Ho, Lee, Yun-Sil, Jung, Yu-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421900/
https://ncbi.nlm.nih.gov/pubmed/28212561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15326
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