Use of second-site suppressor mutations in Drosophila to identify components of the transcriptional machinery.
Isolation of second-site suppressor mutations provides a powerful method for identifying (i) genes that encode proteins that interact and (ii) domains within the interacting proteins that contact each other. Flies conditionally lethal because they carry mutations in the largest subunit of RNA polyme...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1990
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2352953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4864 |
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