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Dysadherin specific drug conjugates for the treatment of thyroid cancers with aggressive phenotypes

BACKGROUND: EDC1 is a novel type of antibody-drug conjugate which binds and inhibits the Na,K-ATPase on the surface of cancer cells expressing dysadherin. The purpose of this study was to determine the expression of dysadherin in different types of thyroid carcinoma, and evaluate the therapeutic pot...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jang, Samuel, Yu, Xiao-Min, Montemayor-Garcia, Celina, Ahmed, Kamal, Weinlander, Eric, Lloyd, Ricardo V., Dammalapati, Ajitha, Marshall, David, Prudent, James R., Chen, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421862/
https://ncbi.nlm.nih.gov/pubmed/28160550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14904
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