A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source

INTRODUCTION: Advances in high-resolution mass spectrometry have created renewed interest for studying global lipid biochemistry in disease and biological systems. OBJECTIVES: Here, we present an untargeted 30 min. LC-MS/MS platform that utilizes positive/negative polarity switching to perform unbia...

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Udgivet i:Metabolomics
Main Authors: Breitkopf, Susanne B., Ricoult, Stéphane J. H., Yuan, Min, Xu, Ying, Peake, David A., Manning, Brendan D., Asara, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421409/
https://ncbi.nlm.nih.gov/pubmed/28496395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1157-8
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