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Don’t stress about CRF: Assessing the translational failures of CRF(1) antagonists

BACKGROUND: Dr. Athina Markou sought treatments for a common neural substrate shared by depression and drug dependence. Antagonists of corticotropin-releasing factor (CRF) receptors, a target of interest to her, have not reached the clinic despite strong preclinical rationale and sustained translati...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Spierling, Samantha R., Zorrilla, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5420464/
https://ncbi.nlm.nih.gov/pubmed/28265716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4556-2
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