Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease

OBJECTIVE: To identify regional brain metabolic dysfunctions associated with neuropsychiatric symptoms (NPS) in preclinical Alzheimer disease (AD). METHODS: We stratified 115 cognitively normal individuals into preclinical AD (both amyloid and tau pathologies present), asymptomatic at risk for AD (e...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Ng, Kok Pin, Pascoal, Tharick A., Mathotaarachchi, Sulantha, Chung, Chang-Oh, Benedet, Andréa L., Shin, Monica, Kang, Min Su, Li, Xiaofeng, Ba, Maowen, Kandiah, Nagaendran, Rosa-Neto, Pedro, Gauthier, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419982/
https://ncbi.nlm.nih.gov/pubmed/28404803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003916
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