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Prolonged Ischemia Triggers Necrotic Depletion of Tissue Resident Macrophages to Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury

Although mechanisms of immune activation against liver ischemia reperfusion injury (IRI) have been studied extensively, questions regarding liver resident macrophages, i.e., Kupffer cells, remain controversial. Recent progress in the biology of tissue resident macrophages implicates homeostatic func...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yue, Shi, Zhou, Haoming, Wang, Xuehao, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W., Zhai, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419828/
https://ncbi.nlm.nih.gov/pubmed/28289160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601428
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