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SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer

Tumor-associated macrophages (TAMs) play a role in tumor angiogenesis and are recruited into the tumor microenvironment (TME) by secreted chemokines, including Monocyte Chemoattractant Protein-1 (MCP-1/CCL2). Angiogenesis is required to sustain proliferation and enable metastasis of breast cancer (B...

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發表在:PLoS One
Main Authors: Hultgren, Elizabeth M., Patrick, Mitch E., Evans, Rick L., Stoos, Catherine T., Egland, Kristi A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419604/
https://ncbi.nlm.nih.gov/pubmed/28475599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177089
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