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Mutation of Mouse Cyp11a1 Promoter Caused Tissue-Specific Reduction of Gene Expression and Blunted Stress Response without Affecting Reproduction

Steroids are synthesized mainly from the adrenal glands catalyzed by steroidogenic enzymes; the expression of these enzymes is controlled by transcription factor steroidogenic factor-1 (SF-1; NR5A1). To understand the physiological effect of genetic changes on steroid secretion, we used Cre-LoxP and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Endocrinol
मुख्य लेखकों: Shih, Meng-Chun, Hsu, Nai-Chi, Huang, Chen-Che, Wu, Tzong-Shoon, Lai, Pao-Yen, Chung, Bon-chu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Endocrine Society 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419550/
https://ncbi.nlm.nih.gov/pubmed/18174359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0222
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