Dysregulation of Adipose Glutathione Peroxidase 3 in Obesity Contributes to Local and Systemic Oxidative Stress

Glutathione peroxidase 3 (GPx3) accounts for the major antioxidant activity in the plasma. Here, we demonstrate that down-regulation of GPx3 in the plasma of obese subjects is associated with adipose GPx3 dysregulation, resulting from the increase of inflammatory signals and oxidative stress. Althou...

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Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Lee, Yun Sok, Kim, A Young, Choi, Jin Woo, Kim, Min, Yasue, Shintaro, Son, Hee Jung, Masuzaki, Hiroaki, Park, Kyong Soo, Kim, Jae Bum
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2008
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419460/
https://ncbi.nlm.nih.gov/pubmed/18562625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0023
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