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Prolactin Blocks Nuclear Translocation of VDR by Regulating Its Interaction with BRCA1 in Osteosarcoma Cells

Based on their content of prolactin receptors, osteosarcoma cells were predicted to be responsive to prolactin (PRL), but whether PRL would be beneficial or contribute to pathogenesis was unclear. 1,25(OH)(2) vitamin D(3) [1α,25(OH)(2)D(3)] has antiproliferative effects on osteosarcoma cells, and a...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Deng, Changhui, Ueda, Eric, Chen, KuanHui E., Bula, Craig, Norman, Anthony W., Luben, Richard A., Walker, Ameae M.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419306/
https://ncbi.nlm.nih.gov/pubmed/19074549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0075
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