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Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model
BACKGROUND: The impairment of histone acetylation is causally linked to the cognitive decline in Alzheimer’s disease (AD). In addition to histone acetyltransferases (HATs) and histone deacetylases (HDACs), inhibitor of acetyltransferases (INHAT) can also regulate histone acetylation. As a key compon...
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| Publicado no: | Mol Neurodegener |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418850/ https://ncbi.nlm.nih.gov/pubmed/28472990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0178-8 |
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