Molecular mechanism of cardol, isolated from Trigona incisa stingless bee propolis, induced apoptosis in the SW620 human colorectal cancer cell line

BACKGROUND: Cardol is a major bioactive constituent in the Trigona incisa propolis from Indonesia, with a strong in vitro antiproliferative activity against the SW620 colorectal adenocarcinoma cell line (IC(50) of 4.51 ± 0.76 μg/mL). Cardol induced G(0)/G(1) cell cycle arrest and apoptotic cell deat...

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Vydáno v:BMC Pharmacol Toxicol
Hlavní autoři: Kustiawan, Paula Mariana, Lirdprapamongkol, Kriengsak, Palaga, Tanapat, Puthong, Songchan, Phuwapraisirisan, Preecha, Svasti, Jisnuson, Chanchao, Chanpen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418687/
https://ncbi.nlm.nih.gov/pubmed/28472978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0139-4
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