CRISPR-Cpf1 assisted genome editing of Corynebacterium glutamicum

Corynebacterium glutamicum is an important industrial metabolite producer that is difficult to genetically engineer. Although the Streptococcus pyogenes (Sp) CRISPR-Cas9 system has been adapted for genome editing of multiple bacteria, it cannot be introduced into C. glutamicum. Here we report a Fran...

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Udgivet i:Nat Commun
Main Authors: Jiang, Yu, Qian, Fenghui, Yang, Junjie, Liu, Yingmiao, Dong, Feng, Xu, Chongmao, Sun, Bingbing, Chen, Biao, Xu, Xiaoshu, Li, Yan, Wang, Renxiao, Yang, Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418603/
https://ncbi.nlm.nih.gov/pubmed/28469274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15179
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