Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson‐Gilford progeria syndrome

Hutchinson‐Gilford progeria syndrome (HGPS) constitutes a genetic disease wherein an aging phenotype manifests in childhood. Recent studies indicate that reactive oxygen species (ROS) play important roles in HGPS phenotype progression. Thus, pharmacological reduction in ROS levels has been proposed...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Kang, Hyun Tae, Park, Joon Tae, Choi, Kobong, Choi, Hyo Jei Claudia, Jung, Chul Won, Kim, Gyu Ree, Lee, Young‐Sam, Park, Sang Chul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418208/
https://ncbi.nlm.nih.gov/pubmed/28317242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12584
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