Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion

Age‐related declines in skeletal muscle regeneration have been attributed to muscle stem cell (MuSC) dysfunction. Aged MuSCs display a fibrogenic conversion, leading to fibrosis and impaired recovery after injury. Although studies have demonstrated the influence of in vitro substrate characteristics...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Stearns‐Reider, Kristen M., D'Amore, Antonio, Beezhold, Kevin, Rothrauff, Benjamin, Cavalli, Loredana, Wagner, William R., Vorp, David A., Tsamis, Alkiviadis, Shinde, Sunita, Zhang, Changqing, Barchowsky, Aaron, Rando, Thomas A., Tuan, Rocky S., Ambrosio, Fabrisia
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418187/
https://ncbi.nlm.nih.gov/pubmed/28371268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12578
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