Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

Cartilaginous structures are at the core of embryo growth and shaping before the bone forms. Here we report a novel principle of vertebrate cartilage growth that is based on introducing transversally-oriented clones into pre-existing cartilage. This mechanism of growth uncouples the lateral expansio...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Kaucka, Marketa, Zikmund, Tomas, Tesarova, Marketa, Gyllborg, Daniel, Hellander, Andreas, Jaros, Josef, Kaiser, Jozef, Petersen, Julian, Szarowska, Bara, Newton, Phillip T, Dyachuk, Vyacheslav, Li, Lei, Qian, Hong, Johansson, Anne-Sofie, Mishina, Yuji, Currie, Joshua D, Tanaka, Elly M, Erickson, Alek, Dudley, Andrew, Brismar, Hjalmar, Southam, Paul, Coen, Enrico, Chen, Min, Weinstein, Lee S, Hampl, Ales, Arenas, Ernest, Chagin, Andrei S, Fried, Kaj, Adameyko, Igor
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology and Stem Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417851/
https://ncbi.nlm.nih.gov/pubmed/28414273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25902
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