Accurate Quantification of Site-specific Acetylation Stoichiometry Reveals the Impact of Sirtuin Deacetylase CobB on the E. coli Acetylome

Lysine acetylation is a protein posttranslational modification (PTM) that occurs on thousands of lysine residues in diverse organisms from bacteria to humans. Accurate measurement of acetylation stoichiometry on a proteome-wide scale remains challenging. Most methods employ a comparison of chemicall...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Weinert, Brian Tate, Satpathy, Shankha, Hansen, Bogi Karbech, Lyon, David, Jensen, Lars Juhl, Choudhary, Chunaram
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417819/
https://ncbi.nlm.nih.gov/pubmed/28254776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M117.067587
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