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Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing

Until recently, vitamin K antagonists (VKAs) were the mainstay of oral anticoagulant treatment with bleeding as the most prevalent adverse effect. One to four percent of patients experience major bleeding episodes, while clinically relevant bleeding occurs in up to 20%. At this moment no laboratory...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bloemen, Saartje, Zwaveling, Suzanne, ten Cate, Hugo, ten Cate-Hoek, Arina, de Laat, Bas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417600/
https://ncbi.nlm.nih.gov/pubmed/28472104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176967
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