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Connecting high-temperature and low-temperature protein stability and aggregation
Protein aggregation is a long-standing problem for preservation of proteins in both laboratory settings and for commercial biotechnology products. It is well established that heating (cooling) can accelerate (slow) aggregation by populating (depopulating) unfolded or partially unfolded monomer state...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417562/ https://ncbi.nlm.nih.gov/pubmed/28472066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176748 |
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