Improvement of uridine production of Bacillus subtilis by atmospheric and room temperature plasma mutagenesis and high-throughput screening

In the present study, a novel breeding strategy of atmospheric and room temperature plasma (ARTP) mutagenesis was used to improve the uridine production of engineered Bacillus subtilis TD12np. A high-throughput screening method was established using both resistant plates and 96-well microplates to s...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Fan, Xiaoguang, Wu, Heyun, Li, Guoliang, Yuan, Hui, Zhang, Hongchao, Li, Yanjun, Xie, Xixian, Chen, Ning
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417507/
https://ncbi.nlm.nih.gov/pubmed/28472077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176545
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