Structural Determinants of Agonist-Selective Signaling at the sst(2A) Somatostatin Receptor

The clinically used somatostatin (SS-14) analogs octreotide and pasireotide (SOM230) stimulate distinct species-specific patterns of sst(2A) somatostatin receptor phosphorylation and internalization. Like SS-14, octreotide promotes the phosphorylation of at least six carboxyl-terminal serine and thr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Nagel, Falko, Doll, Christian, Pöll, Florian, Kliewer, Andrea, Schröder, Helmut, Schulz, Stefan
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2011
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417258/
https://ncbi.nlm.nih.gov/pubmed/21330405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0407
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