In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases

RNA editing is an essential post-transcriptional process that creates functional mitochondrial mRNAs in Kinetoplastids. Multiprotein editosomes catalyze pre-mRNA cleavage, uridine (U) insertion or deletion, and ligation as specified by guide RNAs. Three functionally and compositionally distinct edit...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Carnes, Jason, McDermott, Suzanne, Anupama, Atashi, Oliver, Brian G., Sather, D. Noah, Stuart, Kenneth
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416837/
https://ncbi.nlm.nih.gov/pubmed/28334821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx116
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