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Large-scale interaction effects reveal missing heritability in schizophrenia, bipolar disorder and posttraumatic stress disorder
Genetic susceptibility factors behind psychiatric disorders typically contribute small effects individually. A possible explanation for the missing heritability is that the effects of common variants are not only polygenic but also non-additive, appearing only when interactions within large groups a...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Transl Psychiatry |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5416702/ https://ncbi.nlm.nih.gov/pubmed/28398343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2017.61 |
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