The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization.

The alpha-like DNA polymerases from bacteriophage phi 29 and other viruses, prokaryotes and eukaryotes contain an amino acid consensus sequence that has been proposed to form part of the dNTP binding site. We have used site-directed mutants to study five of the six highly conserved consecutive amino...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bernad, A, Lázaro, J M, Salas, M, Blanco, L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1990
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC54166/
https://ncbi.nlm.nih.gov/pubmed/2191296
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