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IgG silencing induces apoptosis and suppresses proliferation, migration and invasion in LNCaP prostate cancer cells

Immunoglobulin G (IgG) has been implicated in the progression of various cancers. This study explored the role of IgG in the proliferation, apoptosis, cell cycle and in vitro invasive properties of LNCaP prostate cancer cells. We used IGHG1 small interfering RNA to silence IgG1 expression in LNCaP c...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Xu, Yawen, Chen, Binshen, Zheng, Shaobo, Wen, Yong, Xu, Abai, Xu, Kai, Li, Bingkun, Liu, Chunxiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415809/
https://ncbi.nlm.nih.gov/pubmed/28536629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-016-0029-6
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