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(−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

BACKGROUND: Davallia formosana Hayata is a herb that has been used in Chinese medicine to treat bone diseases, including arthritis, bone fractures and osteoporosis. The rhizome of D. formosana H. has been found to be rich in (−)-Epicatechin 3-O-β-d-allopyranoside (ECAP), which is considered to be th...

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Bibliographic Details
Published in:BMC Complement Altern Med
Main Authors: Hsiao, Hung-Bo, Wu, Jin-Bin, Lin, Wen-Chuan
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415808/
https://ncbi.nlm.nih.gov/pubmed/28468652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-017-1737-9
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