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SWELL1 is a regulator of adipocyte size, insulin signaling and glucose homeostasis

Adipocytes undergo considerable volumetric expansion in the setting of obesity. It has been proposed that such marked increases in adipocyte size may be sensed via adipocyte-autonomous mechanisms to mediate size-dependent intracellular signaling. Here, we show that SWELL1 (LRRC8a), a member of the L...

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Bibliografske podrobnosti
izdano v:Nat Cell Biol
Main Authors: Zhang, Yanhui, Xie, Litao, Gunasekar, Susheel K., Tong, Dan, Mishra, Anil, Gibson, William J., Wang, Chuansong, Fidler, Trevor, Marthaler, Brodie, Klingelhutz, Aloysius, Abel, E. Dale, Samuel, Isaac, Smith, Jessica K., Cao, Lei, Sah, Rajan
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415409/
https://ncbi.nlm.nih.gov/pubmed/28436964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3514
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