SWELL1 is a regulator of adipocyte size, insulin signaling and glucose homeostasis

Adipocytes undergo considerable volumetric expansion in the setting of obesity. It has been proposed that such marked increases in adipocyte size may be sensed via adipocyte-autonomous mechanisms to mediate size-dependent intracellular signaling. Here, we show that SWELL1 (LRRC8a), a member of the L...

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Gepubliceerd in:Nat Cell Biol
Hoofdauteurs: Zhang, Yanhui, Xie, Litao, Gunasekar, Susheel K., Tong, Dan, Mishra, Anil, Gibson, William J., Wang, Chuansong, Fidler, Trevor, Marthaler, Brodie, Klingelhutz, Aloysius, Abel, E. Dale, Samuel, Isaac, Smith, Jessica K., Cao, Lei, Sah, Rajan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415409/
https://ncbi.nlm.nih.gov/pubmed/28436964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3514
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