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Targeted knockdown of polo-like kinase 1 alters metabolic regulation in melanoma

A limited number of studies have indicated an association of the mitotic kinase polo-like kinase 1 (PLK1) and cellular metabolism. Here, employing an inducible RNA interference approach in A375 melanoma cells coupled with a PCR array and multiple validation approaches, we demonstrated that PLK1 alte...

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Publicat a:Cancer Lett
Autors principals: Gutteridge, Rosie Elizabeth Ann, Singh, Chandra K., Ndiaye, Mary Ann, Ahmad, Nihal
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415376/
https://ncbi.nlm.nih.gov/pubmed/28235541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.02.013
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