Toward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery

The success of lentiviral vectors in curing fatal genetic and acquired diseases has opened a new era in human gene therapy. However, variability in the efficacy and safety of this therapeutic approach has been reported in human patients. Consequently, lentiviral-vector-based gene therapy is limited...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Suwanmanee, Thipparat, Ferris, Martin T., Hu, Peirong, Gui, Tong, Montgomery, Stephanie A., Pardo-Manuel de Villena, Fernando, Kafri, Tal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415322/
https://ncbi.nlm.nih.gov/pubmed/28480308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.03.009
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